SBGN Bricks Dictionary

The previous version of the dictionary is available at http://sbgnbricks.sourceforge.net.

Metabolic network

Metabolic reaction

Associated GO terms: GO:0008152 metabolic process

Irreversible reaction

Not applicable Not applicable
     

Reversible reaction

Not applicable Not applicable
     

Catalysis

Associated GO terms: GO:0003824 catalytic activity

Irreversible reaction

Not applicable
           

Irreversible reaction with multiple substrates and products

Not applicable
           

Reversible reaction

Not applicable Not applicable
     

Reversible reaction with multiple substrates and products

Not applicable Not applicable
     

Inhibition

Associated GO terms: GO:0043086 negative regulation of catalytic activity

Irreversible reaction

Not applicable Not applicable
     

Irreversible catalyzed reaction

Not applicable Not applicable
     

Reversible catalyzed reaction

Not applicable Not applicable
     

Irreversible reaction

Signalling network

Associated GO terms: GO:0023052 signaling; GO:0007165 signal transduction; GO:0023051 regulation of signaling

Protein phosphorylation

Associated GO terms: GO:0006468 protein phosphorylation; GO:0001934 positive regulation of protein phosphorylation; GO:0032147 activation of protein kinase activity

           
                 
           

For the AF expression, the assumption is that phosporylation of X leads to its activation. Phosphorylation could also lead to its deactivation, and then the stimulation arc in AF would need to be replaced by an inhibition arc.

In a similar way other types of post-translational modifications can be expressed:

Acetylation     Ac     SBO:0000215                 Palmytoylation     Pa     SBO:0000218
Glycosylation     G     SBO:0000217                 Prenylation     Pr     SBO:0000221
Hydroxylation     OH     SBO:0000233                 Protonation     H     SBO:0000212
Methylation     Me     SBO:0000214                 Sulfation     S     SBO:0000220
Myristoylation     My     SBO:0000219                 Ubiquitination     Ub     SBO:0000224

Protein dephosphorylation

                 
                 
                 

For the AF expression, the assumption is that dephosporylation of X leads to its deactivation. Dephosphorylation could also lead to its activation, and then the inhibition arc in AF would need to be replaced by a stimulation arc.

Oligomerisation

Associated GO terms: GO:0051259 protein complex oligomerization

           

For the AF expression, the assumption is that the dimer X/X has some activity.

Complex association

Associated GO terms: GO:0065003 protein-containing complex assembly

                 

For the AF expression, the assumption is that the complex X/Y has some activity.

Complex dissociation

Associated GO terms: GO:0032984 protein-containing complex disassembly

Not applicable
           

Gene regulatory network

Transcription

Associated GO terms: GO:0006351 transcription, DNA-templated; GO:0009299 mRNA transcription

                 

Regulation of transcription by a transcription factor

Associated GO terms: GO:0006351 transcription, DNA-templated; GO:0065004 protein-DNA complex assembly; GO:0009299 mRNA transcription; GO:0006355 regulation of transcription, DNA-templated

                 

Translation

Associated GO terms: GO:0006412 translation

                 

For the AF expression, the assumption is that protein X has some activity.

Transport

Associated GO terms: GO:0006810 transport

Passive transport

                 

Active transport

                 

For the AF expression, the assumption is that X has some activity in the nucleus.

Functional genomics

Associated GO terms: GO:0008150 biological_process

Not applicable Not applicable